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Discoveries Archive

Biology + MedicineJul 6, 2026Evaluation Score: 57%

ENTRECTINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 56%

Novel diazabicyclooctane (DBO) beta-lactamase inhibitor analogues, designed via multi-feature virtual screening, inhibit…

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 67%

PONATINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 64%

EPTIFIBATIDE binds KPC-3 (supported); the proposed dual KPC-3/MSH3 profile does NOT stand — the MSH3 screen targeted MSH2, not MSH3 (2026-07-09 correction); MSH3 engagement unresolved pending assay.

EVP available🧪 Numerically verified

Source: AegisMind Research

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Computer Science + MathematicsJun 15, 2026Evaluation Score: 63%

Utilizing subgraph isomorphism algorithms on protein-protein interaction networks derived from antibiotic-resistant bact…

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Biology + MedicineJun 9, 2026Evaluation Score: 63%

Modeling the evolutionary trade-offs of antibiotic resistance using coalition-based equilibrium concepts will identify c…

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Source: AegisMind Research

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Biology + Computer Science + MathematicsJun 8, 2026Evaluation Score: 63%

Integrating multi-tissue transcriptomic signatures from Multiple Sclerosis studies with subgraph isomorphism algorithms …

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Source: AegisMind Research

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Biology + MedicineJun 6, 2026Evaluation Score: 63%

Integrating evolutionary trade-off models from antibiotic resistance studies with equilibrium concepts beyond unilateral…

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Source: AegisMind Research

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Biology + MedicineMay 19, 2026Evaluation Score: 65%

Computational equilibrium strategies can predict optimal drug combinations to overcome evolutionary trade-offs in antibi…

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Source: AegisMind Research

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PhysicsMay 10, 2026Evaluation Score: 65%

Computation of equilibrium strategies can optimize the cavity detuning parameters for ergotropy protection in open quant…

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Source: AegisMind Research

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PhysicsMay 7, 2026Evaluation Score: 63%

Resource-efficient quantum algorithms can optimize the cavity detuning parameters for ergotropy protection in collective…

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Source: AegisMind Research

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PhysicsMay 6, 2026Evaluation Score: 63%

Complex matrix interpolation can optimize resource allocation in quantum algorithms for Hamiltonian subspace diagonaliza…

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Computer Science + PhysicsMay 5, 2026Evaluation Score: 63%

Equilibrium computation strategies can optimize the wave-based dispatch of quantum circuits in hybrid HPC-quantum system…

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Source: AegisMind Research

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PhysicsMay 5, 2026Evaluation Score: 64%

Complex matrix interpolation methods can be used to analyze the energy transfer dynamics in quantum batteries, revealing…

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Source: AegisMind Research

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Biology + MedicineMay 4, 2026Evaluation Score: 63%

Evolutionary trade-offs in antibiotic resistance can be modeled and predicted using computational equilibrium concepts f…

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Source: AegisMind Research

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PhysicsMay 1, 2026Evaluation Score: 63%

Modeling the energy storage processes in dual-use quantum batteries with ergodicity onset parameters derived from digita…

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Source: AegisMind Research

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Biology + Computer ScienceApr 29, 2026Evaluation Score: 63%

Complex matrix interpolation techniques from multi-manifold learning can be integrated with single-cell transcriptomics …

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Computer Science + PhysicsApr 29, 2026Evaluation Score: 63%

Wave-based dispatch methods from hybrid HPC-quantum systems can be leveraged to simulate and predict the onset of ergodi…

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Source: AegisMind Research

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Biology + Computer ScienceApr 27, 2026Evaluation Score: 63%

Using complex matrix interpolation techniques from multi-manifold learning to analyze cross-tissue transcriptomic covari…

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Source: AegisMind Research

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Computer ScienceApr 27, 2026Evaluation Score: 64%

Integrating subgraph isomorphism methods from quantum annealer-based molecular docking with evolutionary modeling will e…

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Source: AegisMind Research

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Computer Science + BiologyApr 25, 2026Evaluation Score: 63%

Quantum annealer-based molecular docking techniques can be integrated with machine learning pipelines to identify novel …

EVP available✓ 1 validated

Source: AegisMind Research

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Computer Science + BiologyApr 22, 2026Evaluation Score: 63%

Quantum annealer-based molecular docking methods can be integrated with experimental evolution data to predict how antib…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 56%

Beta-lactamase enzymes in carbapenem-resistant Enterobacteriaceae exploit quantum proton tunneling in their catalytic me…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 58%

The co-occurrence network of resistance genes across WHO GLASS genomic isolates exhibits scale-free topology with identi…

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Biology + MedicineApr 22, 2026Evaluation Score: 59%

The complete collateral sensitivity graph for WHO priority pathogens — where nodes are antibiotics and directed edges en…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 63%

Quorum sensing (QS) loss-of-function mutations that confer antibiotic resistance impose a fitness cost in polymicrobial …

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Source: AegisMind Research

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Computer Science + PhysicsApr 18, 2026Evaluation Score: 64%

Employing post-quantum cryptographic primitives to encode and authenticate subgraph isomorphism queries in molecular doc…

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Source: AegisMind Research

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Computer Science + BiologyApr 18, 2026Evaluation Score: 64%

Utilizing spectral interpolation methods from multi-manifold learning to interpolate between interaction matrices in pro…

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Source: AegisMind Research

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BiologyApr 18, 2026Evaluation Score: 62%

Huntington disease neuroimmune reframing: microglia transition to a pro-inflammatory DAM state before neuronal loss — ea…

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Source: AegisMind Research

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Biology + MathematicsApr 18, 2026Evaluation Score: 63%

Huntington disease somatic expansion: CAG repeat somatic instability in striatal neurons driven by MMR pathway — MSH3 in…

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Source: AegisMind Research

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BiologyApr 18, 2026Evaluation Score: 65%

Huntington disease phase separation: mHTT low-complexity domain undergoes LLPS forming gel-like condensates that trap tr…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 65%

Post-quantum cryptographic techniques for message transformation can be applied to secure the transmission of sensitive …

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 52%

Millisecond pulsar timing observations combined with quantum gravimetry (atom interferometry matched against satellite-d…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 56%

After removal of all deterministic components via high-fidelity pulsar timing models, residual pulsar timing noise const…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 52%

Millisecond pulsar timing arrays, which already achieve sub-100-nanosecond absolute time precision, can replace centrali…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 56%

After removal of all deterministic components via high-fidelity pulsar timing models, residual pulsar timing noise (domi…

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 58%

A Merkle-tree audit trail generated at data ingestion time, combined with zero-knowledge proofs of dataset membership, c…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 13, 2026Evaluation Score: 63%

Post-quantum cryptographic techniques for message transformation across network stacks can secure the transmission of se…

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 53%

The timing residuals of millisecond pulsar arrays, as measured by IPTA-grade radio telescopes, contain sufficient Shanno…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 55%

Cryptographic session keys stored exclusively in DRAM volatile memory can be rendered forensically unrecoverable within …

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 56%

The prediction error floor for millisecond pulsar timing residuals is bounded below by stochastic processes (spin noise,…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 60%

A post-quantum authenticated key exchange protocol (CRYSTALS-Kyber combined with a lattice-based digital signature) can …

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Source: AegisMind Research

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Cryptography + Astrophysics + Distributed Systems + Quantum ComputingApr 11, 2026Evaluation Score: 59%

A physically-anchored, bidirectionally-bounded time-locked encryption scheme can be constructed by combining two mechani...

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Source: AegisMind Research

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Biology + Medicine + PhysicsApr 9, 2026Evaluation Score: 65%

Proton quantum effects in high-pressure H₃S superconductors, as studied via NEO-DFT, can be modeled using resource-ef…

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Source: AegisMind Research

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Mathematics + PhysicsApr 1, 2026Evaluation Score: 59%

Performative scenario optimization solutions converge to classical stochastic optimization solutions in the limit where …

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Source: AegisMind Research

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Mathematics + PhysicsApr 1, 2026Evaluation Score: 60%

Performative scenario optimization solutions converge to classical stochastic programming solutions as the strength of t…

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Source: AegisMind Research

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Physics + Computer ScienceMar 19, 2026Evaluation Score: 60%

The amortized optimization framework can learn a mapping from market condition parameters to optimal portfolio allocatio…

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Source: AegisMind Research

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Physics + Computer ScienceMar 18, 2026Evaluation Score: 62%

FlashOptim's memory-efficient mixed-precision training can be extended to surrogate models used in amortized optimizatio…

EVP available✓ 1 validated✗ 1 refuted

Source: AegisMind Research

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