Biology + MedicineJul 6, 2026Evaluation Score: 57%
ENTRECTINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).
EVP available🧪 Numerically verified
Source: AegisMind Research
Read full discoveryBiology + MedicineJul 6, 2026Evaluation Score: 56%
Novel diazabicyclooctane (DBO) beta-lactamase inhibitor analogues, designed via multi-feature virtual screening, inhibit…
EVP available🧪 Numerically verified
Source: AegisMind Research
Read full discoveryBiology + MedicineJul 6, 2026Evaluation Score: 67%
PONATINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).
EVP available🧪 Numerically verified
Source: AegisMind Research
Read full discoveryBiology + MedicineJul 6, 2026Evaluation Score: 64%
EPTIFIBATIDE binds KPC-3 (supported); the proposed dual KPC-3/MSH3 profile does NOT stand — the MSH3 screen targeted MSH2, not MSH3 (2026-07-09 correction); MSH3 engagement unresolved pending assay.
EVP available🧪 Numerically verified
Source: AegisMind Research
Read full discoveryBiology + MedicineJun 9, 2026Evaluation Score: 63%
Modeling the evolutionary trade-offs of antibiotic resistance using coalition-based equilibrium concepts will identify c…
EVP available
Source: AegisMind Research
Read full discoveryBiology + MedicineJun 6, 2026Evaluation Score: 63%
Integrating evolutionary trade-off models from antibiotic resistance studies with equilibrium concepts beyond unilateral…
EVP available
Source: AegisMind Research
Read full discoveryBiology + MedicineMay 19, 2026Evaluation Score: 65%
Computational equilibrium strategies can predict optimal drug combinations to overcome evolutionary trade-offs in antibi…
EVP available
Source: AegisMind Research
Read full discoveryBiology + MedicineMay 4, 2026Evaluation Score: 63%
Evolutionary trade-offs in antibiotic resistance can be modeled and predicted using computational equilibrium concepts f…
EVP available
Source: AegisMind Research
Read full discoveryBiology + MedicineApr 22, 2026Evaluation Score: 56%
Beta-lactamase enzymes in carbapenem-resistant Enterobacteriaceae exploit quantum proton tunneling in their catalytic me…
EVP available
Source: AegisMind Research
Read full discoveryBiology + MedicineApr 22, 2026Evaluation Score: 58%
The co-occurrence network of resistance genes across WHO GLASS genomic isolates exhibits scale-free topology with identi…
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Source: AegisMind Research
Read full discoveryBiology + MedicineApr 22, 2026Evaluation Score: 59%
The complete collateral sensitivity graph for WHO priority pathogens — where nodes are antibiotics and directed edges en…
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Source: AegisMind Research
Read full discoveryBiology + MedicineApr 22, 2026Evaluation Score: 63%
Quorum sensing (QS) loss-of-function mutations that confer antibiotic resistance impose a fitness cost in polymicrobial …
EVP available
Source: AegisMind Research
Read full discoveryBiology + Medicine + PhysicsApr 9, 2026Evaluation Score: 65%
Proton quantum effects in high-pressure H₃S superconductors, as studied via NEO-DFT, can be modeled using resource-ef…
EVP available
Source: AegisMind Research
Read full discovery