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Discoveries Archive

Biology + MedicineJul 6, 2026Evaluation Score: 57%

ENTRECTINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 56%

Novel diazabicyclooctane (DBO) beta-lactamase inhibitor analogues, designed via multi-feature virtual screening, inhibit…

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 67%

PONATINIB is predicted to bind the MSH3 ATPase Walker-A pocket, but MSH3-SELECTIVE inhibition is NOT established (binds an unrelated ATPase as tightly); original evidence targeted MSH2 — pending a biochemical assay + counter-screen (2026-07-09 correction).

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJul 6, 2026Evaluation Score: 64%

EPTIFIBATIDE binds KPC-3 (supported); the proposed dual KPC-3/MSH3 profile does NOT stand — the MSH3 screen targeted MSH2, not MSH3 (2026-07-09 correction); MSH3 engagement unresolved pending assay.

EVP available🧪 Numerically verified

Source: AegisMind Research

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Biology + MedicineJun 9, 2026Evaluation Score: 63%

Modeling the evolutionary trade-offs of antibiotic resistance using coalition-based equilibrium concepts will identify c…

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Source: AegisMind Research

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Biology + Computer Science + MathematicsJun 8, 2026Evaluation Score: 63%

Integrating multi-tissue transcriptomic signatures from Multiple Sclerosis studies with subgraph isomorphism algorithms …

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Source: AegisMind Research

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Biology + MedicineJun 6, 2026Evaluation Score: 63%

Integrating evolutionary trade-off models from antibiotic resistance studies with equilibrium concepts beyond unilateral…

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Source: AegisMind Research

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Biology + MedicineMay 19, 2026Evaluation Score: 65%

Computational equilibrium strategies can predict optimal drug combinations to overcome evolutionary trade-offs in antibi…

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Source: AegisMind Research

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Biology + MedicineMay 4, 2026Evaluation Score: 63%

Evolutionary trade-offs in antibiotic resistance can be modeled and predicted using computational equilibrium concepts f…

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Source: AegisMind Research

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Biology + Computer ScienceApr 29, 2026Evaluation Score: 63%

Complex matrix interpolation techniques from multi-manifold learning can be integrated with single-cell transcriptomics …

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Source: AegisMind Research

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Biology + Computer ScienceApr 27, 2026Evaluation Score: 63%

Using complex matrix interpolation techniques from multi-manifold learning to analyze cross-tissue transcriptomic covari…

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Source: AegisMind Research

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Computer Science + BiologyApr 25, 2026Evaluation Score: 63%

Quantum annealer-based molecular docking techniques can be integrated with machine learning pipelines to identify novel …

EVP available1 validated

Source: AegisMind Research

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Computer Science + BiologyApr 22, 2026Evaluation Score: 63%

Quantum annealer-based molecular docking methods can be integrated with experimental evolution data to predict how antib…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 56%

Beta-lactamase enzymes in carbapenem-resistant Enterobacteriaceae exploit quantum proton tunneling in their catalytic me…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 58%

The co-occurrence network of resistance genes across WHO GLASS genomic isolates exhibits scale-free topology with identi…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 59%

The complete collateral sensitivity graph for WHO priority pathogens — where nodes are antibiotics and directed edges en…

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Source: AegisMind Research

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Biology + MedicineApr 22, 2026Evaluation Score: 63%

Quorum sensing (QS) loss-of-function mutations that confer antibiotic resistance impose a fitness cost in polymicrobial …

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Source: AegisMind Research

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Computer Science + BiologyApr 18, 2026Evaluation Score: 64%

Utilizing spectral interpolation methods from multi-manifold learning to interpolate between interaction matrices in pro…

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Source: AegisMind Research

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BiologyApr 18, 2026Evaluation Score: 62%

Huntington disease neuroimmune reframing: microglia transition to a pro-inflammatory DAM state before neuronal loss — ea…

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Source: AegisMind Research

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Biology + MathematicsApr 18, 2026Evaluation Score: 63%

Huntington disease somatic expansion: CAG repeat somatic instability in striatal neurons driven by MMR pathway — MSH3 in…

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Source: AegisMind Research

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BiologyApr 18, 2026Evaluation Score: 65%

Huntington disease phase separation: mHTT low-complexity domain undergoes LLPS forming gel-like condensates that trap tr…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 65%

Post-quantum cryptographic techniques for message transformation can be applied to secure the transmission of sensitive …

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 52%

Millisecond pulsar timing observations combined with quantum gravimetry (atom interferometry matched against satellite-d…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 56%

After removal of all deterministic components via high-fidelity pulsar timing models, residual pulsar timing noise const…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 52%

Millisecond pulsar timing arrays, which already achieve sub-100-nanosecond absolute time precision, can replace centrali…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 56%

After removal of all deterministic components via high-fidelity pulsar timing models, residual pulsar timing noise (domi…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 14, 2026Evaluation Score: 58%

A Merkle-tree audit trail generated at data ingestion time, combined with zero-knowledge proofs of dataset membership, c…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 13, 2026Evaluation Score: 63%

Post-quantum cryptographic techniques for message transformation across network stacks can secure the transmission of se…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 53%

The timing residuals of millisecond pulsar arrays, as measured by IPTA-grade radio telescopes, contain sufficient Shanno…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 55%

Cryptographic session keys stored exclusively in DRAM volatile memory can be rendered forensically unrecoverable within …

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 56%

The prediction error floor for millisecond pulsar timing residuals is bounded below by stochastic processes (spin noise,…

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Source: AegisMind Research

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Computer Science + Biology + PhysicsApr 12, 2026Evaluation Score: 60%

A post-quantum authenticated key exchange protocol (CRYSTALS-Kyber combined with a lattice-based digital signature) can …

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Source: AegisMind Research

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Biology + Medicine + PhysicsApr 9, 2026Evaluation Score: 65%

Proton quantum effects in high-pressure H₃S superconductors, as studied via NEO-DFT, can be modeled using resource-ef…

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Source: AegisMind Research

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