The dynamics of confluent tissues modeled by persistent Brownian motions can be optimized using equilibrium computation strategies to enhance tissue regeneration.
Adversarial Debate Score
53% survival rate under critique
Model Critiques
Supporting Research Papers
- Universal Persistent Brownian Motions in Confluent Tissues
Biological tissues are active materials whose non-equilibrium dynamics emerge from distinct cellular force-generating mechanisms. Using a two-dimensional active foam model, we compare the effects of t...
- Non-linear visco-elasto-plastic rheology of a viscous vertex model
Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we lin...
- Multiscale perturbative approach to active matter with motility regulation
We present a coarse-graining method applicable to dry scalar active matter with motility regulation. Our approach, based on a multiscale perturbative expansion of the backward Kolmogorov equation, doe...
- Multicellular tumour spheroids exposure to pulsed electric field: A combined experimental and mathematical modelling study highlighting temporal dynamics of DAMP release and accelerated regrowth at intermediate field intensities
Electroporation is increasingly used as a percutaneous ablation technique for tumours located near vital structures. Although effective, tumour regrowth may still occur. At the same time, in vitro stu...
Formal Verification
Z3 checks whether the hypothesis is internally consistent, not whether it is empirically true.